A set of monomeric near-infrared fluorescent proteins for multicolor imaging across scales

Bright monomeric near-infrared (NIR) fluorescent proteins (FPs) are in high demand as protein tags for multicolor microscopy and in vivo imaging. Here we apply rational design to engineer a complete set of monomeric NIR FPs, which are the brightest genetically encoded NIR probes. We demonstrate that...

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Udgivet i:Nat Commun
Main Authors: Matlashov, Mikhail E., Shcherbakova, Daria M., Alvelid, Jonatan, Baloban, Mikhail, Pennacchietti, Francesca, Shemetov, Anton A., Testa, Ilaria, Verkhusha, Vladislav V.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957686/
https://ncbi.nlm.nih.gov/pubmed/31932632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13897-6
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