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Functional analysis of Rossmann-like domains reveals convergent evolution of topology and reaction pathways

Rossmann folds are ancient, frequently diverged domains found in many biological reaction pathways where they have adapted for different functions. Consequently, discernment and classification of their homologous relations and function can be complicated. We define a minimal Rossmann-like structure...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Medvedev, Kirill E., Kinch, Lisa N., Schaeffer, R. Dustin, Grishin, Nick V.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957218/
https://ncbi.nlm.nih.gov/pubmed/31869345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007569
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