Astrovirus replication in human intestinal enteroids reveals multi-cellular tropism and an intricate host innate immune landscape

Human astroviruses (HAstV) are understudied positive-strand RNA viruses that cause gastroenteritis mostly in children and the elderly. Three clades of astroviruses, classic, MLB-type and VA-type have been reported in humans. One limitation towards a better understanding of these viruses has been the...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Kolawole, Abimbola O., Mirabelli, Carmen, Hill, David R., Svoboda, Sophia A., Janowski, Andrew B., Passalacqua, Karla D., Rodriguez, Benancio N., Dame, Michael K., Freiden, Pamela, Berger, Ryan P., Vu, Diem-lan, Hosmillo, Myra, O’Riordan, Mary X. D., Schultz-Cherry, Stacey, Guix, Susana, Spence, Jason R., Wang, David, Wobus, Christiane E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957189/
https://ncbi.nlm.nih.gov/pubmed/31671153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008057
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