Hesperidin improves insulin resistance via down-regulation of inflammatory responses: Biochemical analysis and in silico validation

Leptin resistance and co-existing insulin resistance is considered as hallmark of diet-induced obesity. Here, we investigated therapeutic potential of hesperidin to improve leptin and insulin resistance using high fat diet (HFD)-induced obese experimental animal model. We also performed in silico st...

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Publicat a:PLoS One
Autors principals: Rehman, Kanwal, Munawar, Syeda Mehak, Akash, Muhammad Sajid Hamid, Buabeid, Manal Ali, Chohan, Tahir Ali, Tariq, Muhammad, Jabeen, Komal, Arafa, El-Shaimaa A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957178/
https://ncbi.nlm.nih.gov/pubmed/31929574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0227637
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