Screening human embryos for polygenic traits has limited utility

The increasing proportion of variance in human complex traits explained by polygenic scores, along with progress in preimplantation genetic diagnosis, suggest the possibility of screening embryos for traits such as height or cognitive ability. However, the expected outcomes of embryo screening are u...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell
Prif Awduron: Karavani, Ehud, Zuk, Or, Zeevi, Danny, Barzilai, Nir, Stefanis, Nikos C., Hatzimanolis, Alex, Smyrnis, Nikolaos, Avramopoulos, Dimitrios, Kruglyak, Leonid, Atzmon, Gil, Lam, Max, Lencz, Todd, Carmi, Shai
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957074/
https://ncbi.nlm.nih.gov/pubmed/31761530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.10.033
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