Selective Intratumoral Drug Release and Simultaneous Inhibition of Oxidative Stress by a Highly Reductive Nanosystem and Its Application as an Anti-tumor Agent

Excessive oxidative stress is always associated with the serious side effects of chemotherapy. In the current study, we developed a vitamin E based strongly reductive nanosystem to increase the loading efficiency of docetaxel (DTX, DTX-VNS), reduce its side toxicity and enhance the antitumor effect....

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Zhu, Chunqi, Luo, Lihua, jiang, Xindong, Jiang, Mengshi, Luo, Zhenyu, Li, Xiang, Qiu, Weigen, Jin, Zhaolei, Shen, Tianxiang, Li, Chunlong, Li, Qingpo, Qiu, Yunqing, You, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956823/
https://ncbi.nlm.nih.gov/pubmed/31938058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.38627
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