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Fructose-1,6-bisphosphatase loss modulates STAT3-dependent expression of PD-L1 and cancer immunity

Rationale: Abnormal expression of programmed death-1 (PD-1) ligand-1(PD-L1) in cancer cells plays a crucial role in cancer immune evasion and progression. The immune checkpoint molecules PD-1 and PD-L1 have been targeted for cancer treatment with significant benefits for cancer patients. However, th...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Wang, Bo, Zhou, Yingke, Zhang, Jun, Jin, Xin, Wu, Heshui, Huang, Haojie
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956820/
https://ncbi.nlm.nih.gov/pubmed/31938049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.38137
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