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Bayesian GWAS with Structured and Non-Local Priors

MOTIVATION: The flexibility of a Bayesian framework is promising for GWAS, but current approaches can benefit from more informative prior models. We introduce a novel Bayesian approach to GWAS, called Structured and Non-Local Priors (SNLPs) GWAS, that improves over existing methods in two important...

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Bibliografski detalji
Izdano u:Bioinformatics
Glavni autori: Kaplan, Adam, Lock, Eric F, Fiecas, Mark
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956774/
https://ncbi.nlm.nih.gov/pubmed/31651034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz518
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