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The impact of various seed, accessibility and interaction constraints on sRNA target prediction- a systematic assessment

BACKGROUND: Seed and accessibility constraints are core features to enable highly accurate sRNA target screens based on RNA-RNA interaction prediction. Currently, available tools provide different (sets of) constraints and default parameter sets. Thus, it is hard to impossible for users to estimate...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Raden, Martin, Müller, Teresa, Mautner, Stefan, Gelhausen, Rick, Backofen, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956497/
https://ncbi.nlm.nih.gov/pubmed/31931703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3143-4
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