Cysteine-Targeted Insecticides against A. gambiae Acetylcholinesterase Are Neither Selective nor Reversible Inhibitors

[Image: see text] Acetylcholinesterase cysteine-targeted insecticides against malaria vector Anopheles gambia and other mosquitos have already been introduced. We have applied the olefin metathesis for the preparation of cysteine-targeted insecticides in high yields. The prepared compounds with eith...

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Publicat a:ACS Med Chem Lett
Autors principals: Gorecki, Lukas, Andrys, Rudolf, Schmidt, Monika, Kucera, Tomas, Psotka, Miroslav, Svobodova, Barbora, Hrabcova, Veronika, Hepnarova, Vendula, Bzonek, Petr, Jun, Daniel, Kuca, Kamil, Korabecny, Jan, Musilek, Kamil
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2019
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956356/
https://ncbi.nlm.nih.gov/pubmed/31938465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00477
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