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Is age‐related increase of chromosome segregation errors in mammalian oocytes caused by cohesin deterioration?

BACKGROUND: Mammalian oocytes initiate meiosis in fetal ovary and are arrested at dictyate stage in prophase I for a long period. It is known that incidence of chromosome segregation errors in oocytes increases with advancing age, but the molecular mechanism underlying this phenomenon has not been c...

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Detalhes bibliográficos
Publicado no:Reprod Med Biol
Autor principal: Lee, Jibak
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955592/
https://ncbi.nlm.nih.gov/pubmed/31956283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rmb2.12299
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