Multicentre, non-interventional study of the efficacy and tolerability of linaclotide in the treatment of irritable bowel syndrome with constipation in primary, secondary and tertiary centres: the Alpine study

OBJECTIVES: We evaluated the effectiveness and tolerability of linaclotide, a minimally absorbed guanylate cyclase-C agonist, in patients with irritable bowel syndrome with constipation (IBS-C) in routine clinical practice. SETTING: A multicentre, non-interventional study conducted between December...

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Detalles Bibliográficos
Publicado en:BMJ Open
Autores principales: Pohl, Daniel, Fried, Michael, Lawrance, Dominic, Beck, Elmar, Hammer, Heinz F.
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 2019
Materias:
Gastroenterology and Hepatology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955540/
https://ncbi.nlm.nih.gov/pubmed/31892640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2018-025627
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