Study protocol for a phase II, multicentre, prospective, non-randomised clinical trial to assess the safety and efficacy of infusing allogeneic activated and expanded natural killer cells as consolidation therapy for paediatric acute myeloblastic leukaemia

INTRODUCTION: Acute myeloblastic leukaemia (AML) constitutes the second most common haematological malignancy in the paediatric population. Current treatment regimens are based on the administration of polychemotherapy, combining high doses of cytarabine with anthracyclines and topoisomerase inhibit...

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Dades bibliogràfiques
Publicat a:BMJ Open
Autors principals: Muñoz Builes, Mario, Vela Cuenca, María, Fuster Soler, Jose L, Astigarraga, Itziar, Pascual Martínez, Antonia, Vagace Valero, Jose M, Tong, Hoi Y, Valentín Quiroga, Jaime, Fernández Casanova, Lucía, Escudero López, Adela, Sisinni, Luisa, Blanquer, Miguel, Mirones Aguilar, Isabel, González Martínez, Berta, Borobia, Alberto M, Pérez-Martínez, Antonio
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2020
Matèries:
Haematology (Incl Blood Transfusion)
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955478/
https://ncbi.nlm.nih.gov/pubmed/31919123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2019-029642
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