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Accurate and rapid background estimation in single-molecule localization microscopy using the deep neural network BGnet

Background fluorescence, especially when it exhibits undesired spatial features, is a primary factor for reduced image quality in optical microscopy. Structured background is particularly detrimental when analyzing single-molecule images for 3-dimensional localization microscopy or single-molecule t...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Möckl, Leonhard, Roy, Anish R., Petrov, Petar N., Moerner, W. E.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955367/
https://ncbi.nlm.nih.gov/pubmed/31871202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1916219117
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