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Lessons from equilibrium statistical physics regarding the assembly of protein complexes

Cellular functions are established through biological evolution, but are constrained by the laws of physics. For instance, the physics of protein folding limits the lengths of cellular polypeptide chains. Consequently, many cellular functions are carried out not by long, isolated proteins, but rathe...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Sartori, Pablo, Leibler, Stanislas
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955335/
https://ncbi.nlm.nih.gov/pubmed/31871201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911028117
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