An inhibitor of complement C5 provides structural insights into activation

The complement system is a crucial part of innate immune defenses against invading pathogens. The blood-meal of the tick Rhipicephalus pulchellus lasts for days, and the tick must therefore rely on inhibitors to counter complement activation. We have identified a class of inhibitors from tick saliva...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Reichhardt, Martin P., Johnson, Steven, Tang, Terence, Morgan, Thomas, Tebeka, Nchimunya, Popitsch, Niko, Deme, Justin C., Jore, Matthijs M., Lea, Susan M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2020
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955305/
https://ncbi.nlm.nih.gov/pubmed/31871188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909973116
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