Disruption of the Dimer-Dimer Interaction of the Mumps Virus Attachment Protein Head Domain, Aided by an Anion Located at the Interface, Compromises Membrane Fusion Triggering

Mumps virus (MuV), an enveloped negative-strand RNA virus belonging to the family Paramyxoviridae, enters the host cell through membrane fusion mediated by two viral envelope proteins, an attachment protein hemagglutinin-neuraminidase (MuV-HN) and a fusion (F) protein. However, how the binding of Mu...

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Vydáno v:J Virol
Hlavní autoři: Kubota, Marie, Okabe, Iori, Nakakita, Shin-ichi, Ueo, Ayako, Shirogane, Yuta, Yanagi, Yusuke, Hashiguchi, Takao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955283/
https://ncbi.nlm.nih.gov/pubmed/31619562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01732-19
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