The Caenorhabditis elegans RIG-I Homolog DRH-1 Mediates the Intracellular Pathogen Response upon Viral Infection

Mammalian retinoic acid-inducible gene I (RIG-I)-like receptors detect viral double-stranded RNA (dsRNA) and 5′-triphosphorylated RNA to activate the transcription of interferon genes and promote antiviral defense. The Caenorhabditis elegans RIG-I-like receptor DRH-1 promotes defense through antivir...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Sowa, Jessica N., Jiang, Hongbing, Somasundaram, Lakshmi, Tecle, Eillen, Xu, Guorong, Wang, David, Troemel, Emily R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Cellular Response to Infection
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955277/
https://ncbi.nlm.nih.gov/pubmed/31619561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01173-19
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