Three Amino Acid Changes in Avian Coronavirus Spike Protein Allow Binding to Kidney Tissue

Infectious bronchitis virus (IBV) infects ciliated epithelial cells in the chicken respiratory tract. While some IBV strains replicate locally, others can disseminate to various organs, including the kidney. Here, we elucidate the determinants for kidney tropism by studying interactions between the...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Bouwman, Kim M., Parsons, Lisa M., Berends, Alinda J., de Vries, Robert P., Cipollo, John F., Verheije, Monique H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2020
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955270/
https://ncbi.nlm.nih.gov/pubmed/31694947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01363-19
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