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VAMP8 Contributes to the TRIM6-Mediated Type I Interferon Antiviral Response during West Nile Virus Infection

Several members of the tripartite motif (TRIM) family of E3 ubiquitin ligases regulate immune pathways, including the antiviral type I interferon (IFN-I) system. Previously, we demonstrated that TRIM6 is involved in IFN-I induction and signaling. In the absence of TRIM6, optimal IFN-I signaling is r...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: van Tol, Sarah, Atkins, Colm, Bharaj, Preeti, Johnson, Kendra N., Hage, Adam, Freiberg, Alexander N., Rajsbaum, Ricardo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955268/
https://ncbi.nlm.nih.gov/pubmed/31694946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01454-19
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