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Weak cis and trans Interactions of the Hemagglutinin with Receptors Trigger Fusion Proteins of Neuropathogenic Measles Virus Isolates

Measles virus (MeV) is an enveloped RNA virus bearing two envelope glycoproteins, the hemagglutinin (H) and fusion (F) proteins. Upon receptor binding, the H protein triggers conformational changes of the F protein, causing membrane fusion and subsequent virus entry. MeV may persist in the brain, in...

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Foilsithe in:J Virol
Main Authors: Shirogane, Yuta, Hashiguchi, Takao, Yanagi, Yusuke
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955248/
https://ncbi.nlm.nih.gov/pubmed/31619560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01727-19
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