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Weak cis and trans Interactions of the Hemagglutinin with Receptors Trigger Fusion Proteins of Neuropathogenic Measles Virus Isolates

Measles virus (MeV) is an enveloped RNA virus bearing two envelope glycoproteins, the hemagglutinin (H) and fusion (F) proteins. Upon receptor binding, the H protein triggers conformational changes of the F protein, causing membrane fusion and subsequent virus entry. MeV may persist in the brain, in...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Shirogane, Yuta, Hashiguchi, Takao, Yanagi, Yusuke
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955248/
https://ncbi.nlm.nih.gov/pubmed/31619560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01727-19
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