Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals

A unique property of skeletal muscle is its ability to adapt its mass to changes in activity. Inactivity, as in disuse or aging, causes atrophy, the loss of muscle mass and strength, leading to physical incapacity and poor quality of life. Here, through a combination of transcriptomics and transgene...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Segalés, Jessica, Perdiguero, Eusebio, Serrano, Antonio L., Sousa-Victor, Pedro, Ortet, Laura, Jardí, Mercè, Budanov, Andrei V., Garcia-Prat, Laura, Sandri, Marco, Thomson, David M., Karin, Michael, Hee Lee, Jun, Muñoz-Cánoves, Pura
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955241/
https://ncbi.nlm.nih.gov/pubmed/31929511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13832-9
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