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Lar maintains the homeostasis of the hematopoietic organ in Drosophila by regulating insulin signaling in the niche

Stem cell compartments in metazoa get regulated by systemic factors as well as local stem cell niche-derived factors. However, the mechanisms by which systemic signals integrate with local factors in maintaining tissue homeostasis remain unclear. Employing the Drosophila lymph gland, which harbors d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Kaur, Harleen, Sharma, Shiv Kumar, Mandal, Sudip, Mandal, Lolitika
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955224/
https://ncbi.nlm.nih.gov/pubmed/31784462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.178202
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