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Alpha spending for historical versus surveillance Poisson data with CMaxSPRT
Sequential analysis hypothesis testing is now an important tool for postmarket drug and vaccine safety surveillance. When the number of adverse events accruing in time is assumed to follow a Poisson distribution, and if the baseline Poisson rate is assessed only with uncertainty, the conditional max...
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| Publicado en: | Stat Med |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6955154/ https://ncbi.nlm.nih.gov/pubmed/30689224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.8097 |
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