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Immunotoxicity from checkpoint inhibitor therapy: clinical features and underlying mechanisms

Immune checkpoint inhibition with monoclonal antibodies is becoming increasingly commonplace in cancer medicine, having contributed to a widening of therapeutic options across oncological indications. Disruption of immune tolerance is the key mechanism of action of checkpoint inhibitors and although...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Fessas, Petros, Possamai, Lucia A., Clark, James, Daniels, Ella, Gudd, Cathrin, Mullish, Benjamin H., Alexander, James L., Pinato, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954715/
https://ncbi.nlm.nih.gov/pubmed/31646612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13141
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