Nicotinamide riboside preserves cardiac function in a mouse model of dilated cardiomyopathy

BACKGROUND—: Myocardial metabolic impairment is a major feature in chronic heart failure (HF). As the major coenzyme in fuel oxidation and oxidative phosphorylation and a substrate for enzymes signaling energy stress and oxidative stress response, NAD(+) is emerging as a metabolic target in a number...

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Published in:Circulation
Main Authors: Diguet, Nicolas, Trammell, Samuel AJ, Tannous, Cynthia, Deloux, Robin, Piquereau, Jérôme, Mougenot, Nathalie, Gouge, Anne, Gressette, Mélanie, Manoury, Boris, Blanc, Jocelyne, Breton, Marie, Decaux, Jean-François, Lavery, Gareth, Baczkó, István, Zoll, Joffrey, Garnier, Anne, Li, Zhenlin, Brenner, Charles, Mericskay, Mathias
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954688/
https://ncbi.nlm.nih.gov/pubmed/29217642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.116.026099
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