Silencing of miR-17-5p suppresses cell proliferation and promotes cell apoptosis by directly targeting PIK3R1 in laryngeal squamous cell carcinoma

BACKGROUND: Increasing evidence has suggested that microRNAs (miRNAs) act as key post-transcriptional regulators in tumor progression. Previous studies have confirmed that miR-17-5p functions as an oncogene in multiple cancers and contributes to tumor progression. However, the role and biological fu...

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Veröffentlicht in:Cancer Cell Int
Hauptverfasser: Wang, Jian-Xing, Jia, Xin-Ju, Liu, Yan, Dong, Jin-Hui, Ren, Xiu-Min, Xu, Ou, Liu, Sheng-Hui, Shan, Chun-Guang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Primary Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954602/
https://ncbi.nlm.nih.gov/pubmed/31938022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-1096-3
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