Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing

Variations in transcription start site (TSS) selection reflect diversity of preinitiation complexes and can impact on post-transcriptional RNA fates. Most metazoan polymerase II-transcribed genes carry canonical initiation with pyrimidine/purine (YR) dinucleotide, while translation machinery-associa...

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Publicat a:Nat Commun
Autors principals: Nepal, Chirag, Hadzhiev, Yavor, Balwierz, Piotr, Tarifeño-Saldivia, Estefanía, Cardenas, Ryan, Wragg, Joseph W., Suzuki, Ana-Maria, Carninci, Piero, Peers, Bernard, Lenhard, Boris, Andersen, Jesper B., Müller, Ferenc
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954239/
https://ncbi.nlm.nih.gov/pubmed/31924754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13687-0
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