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MicroRNA-411 and Its 5′-IsomiR Have Distinct Targets and Functions and Are Differentially Regulated in the Vasculature under Ischemia

MicroRNAs are posttranscriptional regulators of gene expression. As microRNAs can target many genes simultaneously, microRNAs can regulate complex multifactorial processes, including post-ischemic neovascularization, a major recovery pathway in cardiovascular disease. MicroRNAs select their target m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther
Hauptverfasser: van der Kwast, Reginald V.C.T., Woudenberg, Tamar, Quax, Paul H.A., Nossent, A. Yaël
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953895/
https://ncbi.nlm.nih.gov/pubmed/31636041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.10.002
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