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Single photon DNA photocleavage at 830 nm by quinoline dicarbocyanine dyes

We have synthesized symmetrical carbocyanine dyes in which two 4-quinolinium rings are joined by a pentamethine bridge that is meso-substituted with H or Cl. Irradiation of the halogenated dye at 830 nm produces hydroxyl radicals that generate DNA direct strand breaks. This represents the first repo...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Basnet, Kanchan, Fatemipouya, Tayebeh, St. Lorenz, Anna, Nguyen, Mindy, Taratula, Oleh, Henary, Maged, Grant, Kathryn B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953408/
https://ncbi.nlm.nih.gov/pubmed/31584046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9cc04751d
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