IGF-1 enhances BMSC viability, migration, and anti-apoptosis in myocardial infarction via secreted frizzled-related protein 2 pathway

BACKGROUND: Bone marrow mesenchymal stem cell (BMSC) transplantation represents a promising therapeutic strategy for ischemic heart disease. However, its effects are hampered by the poor viability of transplanted cells and the hostile microenvironment of the ischemic region. Insulin-like growth fact...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Lin, Mingzhuo, Liu, Xinyue, Zheng, Haoxiao, Huang, Xiaohui, Wu, Yu, Huang, Anqing, Zhu, Hailan, Hu, Yunzhao, Mai, Weiyi, Huang, Yuli
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953226/
https://ncbi.nlm.nih.gov/pubmed/31918758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1544-y
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