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The Role of NF-κB in Physiological Bone Development and Inflammatory Bone Diseases: Is NF-κB Inhibition “Killing Two Birds with One Stone”?

Nuclear factor-κB (NF-κB) is a transcription factor that regulates the expression of various genes involved in inflammation and the immune response. The activation of NF-κB occurs via two pathways: inflammatory cytokines, such as TNF-α and IL-1β, activate the “classical pathway”, and cytokines invol...

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Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Jimi, Eijiro, Takakura, Nana, Hiura, Fumitaka, Nakamura, Ichiro, Hirata-Tsuchiya, Shizu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952937/
https://ncbi.nlm.nih.gov/pubmed/31847314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8121636
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