CD47-SIRPα Signaling Induces Epithelial-Mesenchymal Transition and Cancer Stemness and Links to a Poor Prognosis in Patients with Oral Squamous Cell Carcinoma

Background: Oral squamous cell carcinoma (OSCC), with high mortality rates, is one of the most diagnosed head and neck cancers. Epithelial-to-mesenchymal transition (EMT) and the generation of cancer stem cells (CSCs) are two keys for therapy-resistance, relapse, and distant metastasis. Accumulating...

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Pubblicato in:Cells
Autori principali: Pai, Shin, Bamodu, Oluwaseun Adebayo, Lin, Yen-Kuang, Lin, Chun-Shu, Chu, Pei-Yi, Chien, Ming-Hsien, Wang, Liang-Shun, Hsiao, Michael, Yeh, Chi-Tai, Tsai, Jo-Ting
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952929/
https://ncbi.nlm.nih.gov/pubmed/31861233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8121658
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