Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection

Host dependency factors that are required for influenza A virus infection may serve as therapeutic targets as the virus is less likely to bypass them under drug-mediated selection pressure. Previous attempts to identify host factors have produced largely divergent results, with few overlapping hits...

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Publicado no:Nat Commun
Main Authors: Li, Bo, Clohisey, Sara M., Chia, Bing Shao, Wang, Bo, Cui, Ang, Eisenhaure, Thomas, Schweitzer, Lawrence D., Hoover, Paul, Parkinson, Nicholas J., Nachshon, Aharon, Smith, Nikki, Regan, Tim, Farr, David, Gutmann, Michael U., Bukhari, Syed Irfan, Law, Andrew, Sangesland, Maya, Gat-Viks, Irit, Digard, Paul, Vasudevan, Shobha, Lingwood, Daniel, Dockrell, David H., Doench, John G., Baillie, J. Kenneth, Hacohen, Nir
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952391/
https://ncbi.nlm.nih.gov/pubmed/31919360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13965-x
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