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Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis

Technical problems intrinsic to the purification of preribosome intermediates have limited our understanding of ribosome biosynthesis in humans. Addressing this issue is important given the implication of this biological process in human disease. Here we report a preribosome purification and tagging...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Nieto, Blanca, Gaspar, Sonia G., Moriggi, Giulia, Pestov, Dimitri G., Bustelo, Xosé R., Dosil, Mercedes
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952385/
https://ncbi.nlm.nih.gov/pubmed/31919354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13990-w
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