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Combinatorial chromatin dynamics foster accurate cardiopharyngeal fate choices

During embryogenesis, chromatin accessibility profiles control lineage-specific gene expression by modulating transcription, thus impacting multipotent progenitor states and subsequent fate choices. Subsets of cardiac and pharyngeal/head muscles share a common origin in the cardiopharyngeal mesoderm...

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Bibliographic Details
Published in:eLife
Main Authors: Racioppi, Claudia, Wiechecki, Keira A, Christiaen, Lionel
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952182/
https://ncbi.nlm.nih.gov/pubmed/31746740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49921
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