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Charcot-Leyden Crystals in Eosinophilic Inflammation: Active Cytolysis Leads to Crystal Formation

PURPOSE OF REVIEW: Charcot-Leyden crystals (CLCs), slender bipyramidal hexagonal crystals, were first described by Jean-Martin Charcot in 1853, predating Paul Ehrlich’s “discovery” of eosinophils by 26 years. To date, CLCs are known as a classical hallmark of eosinophilic inflammation. CLC protein e...

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Detalhes bibliográficos
Publicado no:Curr Allergy Asthma Rep
Main Authors: Ueki, Shigeharu, Miyabe, Yui, Yamamoto, Yohei, Fukuchi, Mineyo, Hirokawa, Makoto, Spencer, Lisa A., Weller, Peter F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952074/
https://ncbi.nlm.nih.gov/pubmed/31203469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11882-019-0868-0
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