Human ESC-derived expandable hepatic organoids enable therapeutic liver repopulation and pathophysiological modeling of alcoholic liver injury

We report the generation of human ESC-derived, expandable hepatic organoids (hEHOs) using our newly established method with wholly defined (serum-free, feeder free) media. The hEHOs stably maintain phenotypic features of bipotential liver stem/progenitor cells that can differentiate into functional...

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Foilsithe in:Cell Res
Main Authors: Wang, Shuyong, Wang, Xuan, Tan, Zuolong, Su, Yuxin, Liu, Juan, Chang, Mingyang, Yan, Fang, Chen, Jie, Chen, Tao, Li, Chuanjiang, Hu, Jie, Wang, Yunfang
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6951343/
https://ncbi.nlm.nih.gov/pubmed/31628434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-019-0242-8
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