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Nuclear S-nitrosylation defines an optimal zone for inducing pluripotency

BACKGROUND: We found that cell-autonomous innate immune signaling causes global changes in the expression of epigenetic modifiers to facilitate nuclear reprogramming to pluripotency. A role of S-nitrosylation by inducible NO synthase (iNOS), an important effector of innate immunity, has been previou...

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Bibliografiske detaljer
Udgivet i:Circulation
Main Authors: Chanda, Palas K., Meng, Shu, Lee, Jieun, Leung, Honchiu E., Chen, Kaifu, Cooke, John P.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6951243/
https://ncbi.nlm.nih.gov/pubmed/31412725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.119.042371
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