SOD2 ameliorates pulmonary hypertension in a murine model of sleep apnea via suppressing expression of NLRP3 in CD11b(+) cells

BACKGROUND: High prevalence of obstructive sleep apnea (OSA) in the pulmonary hypertension (PH) population suggests that chronic intermittent hypoxia (CIH) is an important pathogenic factor of PH. However, the exact mechanism of CIH induced PH is not clear. One of the molecules that plays a key role...

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Bibliografiske detaljer
Udgivet i:Respir Res
Main Authors: Fu, Cuiping, Hao, Shengyu, Liu, Zilong, Xie, Liang, Wu, Xu, Wu, Xiaodan, Li, Shanqun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6951024/
https://ncbi.nlm.nih.gov/pubmed/31915037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1270-0
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