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Genetic profiling and cardiovascular phenotypic spectrum in a Chinese cohort of Loeys-Dietz syndrome patients

BACKGROUND: Loeys-Dietz syndrome (LDS) is a rare connective tissue disorder for which 6 genes in the TGF-β pathway have been identified as causative. With the widespread use of genetic testing, the range of known clinical and genetic profiles has broadened, but these features have not been fully elu...

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Detalhes bibliográficos
Publicado no:Orphanet J Rare Dis
Main Authors: Yang, Hang, Ma, Yanyun, Luo, Mingyao, Zhu, Guoyan, Zhang, Yinhui, Li, Binbin, Shu, Chang, Zhou, Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950884/
https://ncbi.nlm.nih.gov/pubmed/31915033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-019-1282-3
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