Engineered exosomes for targeted co-delivery of miR-21 inhibitor and chemotherapeutics to reverse drug resistance in colon cancer

BACKGROUND: 5-Fluorouracil (5-FU) has been commonly prescribed for patients with colorectal cancer (CRC), but resistance to 5-FU is one of the main reasons for failure in CRC. Recently, microRNAs (miRNAs) have been established as a means of reversing the dilemma by regulating signaling pathways invo...

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Detalhes bibliográficos
Publicado no:J Nanobiotechnology
Main Authors: Liang, Gaofeng, Zhu, Yanliang, Ali, Doulathunnisa Jaffar, Tian, Tian, Xu, Huantian, Si, Ke, Sun, Bo, Chen, Baoan, Xiao, Zhongdang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950820/
https://ncbi.nlm.nih.gov/pubmed/31918721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-019-0563-2
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