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Tumor- and mitochondria-targeted nanoparticles eradicate drug resistant lung cancer through mitochondrial pathway of apoptosis

Chemotherapeutic drugs frequently encounter multidrug resistance. ATP from mitochondria helps overexpression of drug efflux pumps to induce multidrug resistance, so mitochondrial delivery as a means of “repurposing’’ chemotherapeutic drugs currently used in the clinic appears to be a worthwhile stra...

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Detalhes bibliográficos
Publicado no:J Nanobiotechnology
Main Authors: Wang, He, Zhang, Fangke, Wen, Huaying, Shi, Wenwen, Huang, Qiudi, Huang, Yugang, Xie, Jiacui, Li, Peiyin, Chen, Jianhai, Qin, Linghao, Zhou, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950814/
https://ncbi.nlm.nih.gov/pubmed/31918714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-019-0562-3
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