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Polymyxin B Loosens Lipopolysaccharide Bilayer but Stiffens Phospholipid Bilayer

Multidrug-resistant Gram-negative bacteria have increased the prevalence of a variety of serious diseases in modern times. Polymyxins are used as the last-line therapeutic options for the treatment of infections. However, the mechanism of action of polymyxins remains in dispute. In this work, we use...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Fu, Lei, Wan, Mingwei, Zhang, Shan, Gao, Lianghui, Fang, Weihai
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950770/
https://ncbi.nlm.nih.gov/pubmed/31812355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.11.008
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