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Cofilin-actin rod formation in experimental stroke is attenuated by therapeutic hypothermia and overexpression of the inducible 70 kD inducible heat shock protein (Hsp70)

BACKGROUND AND PURPOSE: Cofilin-actin rods are covalently linked aggregates of cofilin-1 and actin. Under ischemic conditions, these rods have been observed in neuronal dendrites and axons and may contribute to the loss of these processes. Hypothermia (Hypo) and the 70 kD inducible heat shock protei...

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Bibliografiske detaljer
Udgivet i:Brain Circ
Main Authors: Kurisu, Kota, You, Jesung, Zheng, Zhen, Won, Seok Joon, Swanson, Raymond A, Yenari, Midori A
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer - Medknow 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950512/
https://ncbi.nlm.nih.gov/pubmed/31950099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/bc.bc_52_19
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