A Versatile and Robust Serine Protease Inhibitor Scaffold from Actinia tenebrosa

Serine proteases play pivotal roles in normal physiology and a spectrum of patho-physiological processes. Accordingly, there is considerable interest in the discovery and design of potent serine protease inhibitors for therapeutic applications. This led to concerted efforts to discover versatile and...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Chen, Xingchen, Leahy, Darren, Van Haeften, Jessica, Hartfield, Perry, Prentis, Peter J., van der Burg, Chloé A., Surm, Joachim M., Pavasovic, Ana, Madio, Bruno, Hamilton, Brett R., King, Glenn F., Undheim, Eivind A. B., Brattsand, Maria, Harris, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950308/
https://ncbi.nlm.nih.gov/pubmed/31842369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17120701
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