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Screening of the copy number increase of AKT in lung carcinoma by custom-designed MLPA

Treatments for lung cancer include therapies targeting aberrant oncoproteins, but there remains a high medical need for novel therapies. Our previous studies showed that gene amplification/high-level polysomy of AKT1/2 occurs in more than 10% of lung carcinomas. Here, we describe multiplex ligation-...

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Vydáno v:Int J Clin Exp Pathol
Hlavní autoři: Minegishi, Kentaro, Dobashi, Yoh, Tsubochi, Hiroyoshi, Tokuda, Ryoko, Okudela, Koji, Ooi, Akishi
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949816/
https://ncbi.nlm.nih.gov/pubmed/31934177
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