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Exon sequencing reveals that missense mutation of PBX1 gene may increase the risk of non-syndromic cleft lip/palate

Objective: Non-syndromic oral cleft (NSOC) is one of the most common multifactorial birth defects. A previous animal study showed PBX1 gene knockout mice consequently exhibited complete cleft lip/palate (CL/P). However, little is known about the association between PBX1 and NSOC in humans. This stud...

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Detalles Bibliográficos
Publicado en:Int J Clin Exp Pathol
Main Authors: Ma, Jian, Yin, Bin, Shi, Jia-Yu, Lin, Yan-Song, Duan, Shi-Jun, Shi, Bing, Jia, Zhong-Lin
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949560/
https://ncbi.nlm.nih.gov/pubmed/31934099
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