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Chromatin fibers stabilize nucleosomes under torsional stress

Torsional stress generated during DNA replication and transcription has been suggested to facilitate nucleosome unwrapping and thereby the progression of polymerases. However, the propagation of twist in condensed chromatin remains yet unresolved. Here, we measure how force and torque impact chromat...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kaczmarczyk, Artur, Meng, He, Ordu, Orkide, Noort, John van, Dekker, Nynke H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949304/
https://ncbi.nlm.nih.gov/pubmed/31913285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13891-y
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