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Chromatin fibers stabilize nucleosomes under torsional stress

Torsional stress generated during DNA replication and transcription has been suggested to facilitate nucleosome unwrapping and thereby the progression of polymerases. However, the propagation of twist in condensed chromatin remains yet unresolved. Here, we measure how force and torque impact chromat...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Kaczmarczyk, Artur, Meng, He, Ordu, Orkide, Noort, John van, Dekker, Nynke H.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949304/
https://ncbi.nlm.nih.gov/pubmed/31913285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13891-y
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