Compound 13 activates AMPK-Nrf2 signaling to protect neuronal cells from oxygen glucose deprivation-reoxygenation

Oxygen glucose deprivation-reoxygenation (OGD-R) causes the production of reactive oxygen species (ROS) and oxidative injury in neuronal cells. We tested the potential neuroprotective function of compound 13 (C13), a novel AMP-activated protein kinase (AMPK) activator, against OGD-R. We show that C1...

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Bibliographic Details
Published in:Aging (Albany NY)
Main Authors: Mo, Yanqing, Zhu, Jian-liang, Jiang, Aihua, Zhao, Jing, Ye, Liping, Han, Bin
Format: Artigo
Language:Inglês
Published: Impact Journals 2019
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949105/
https://ncbi.nlm.nih.gov/pubmed/31852839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102534
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